General Hospital Spoilers for Wednesday, October 29 | GH Spoilers 10/29/2025

The October 29th episode of General Hospital promises to shake Port Charles to its core, weaving together heartbreak, betrayal, and dark revelations across multiple storylines — from Curtis’s emotional reckoning with betrayal, to Ronnie’s ruthless takeover of the Quartermaine mansion, Nathan’s dangerous pursuit of truth, and Lulu’s spiraling obsession that threatens to destroy what’s left of her family.

It begins with Curtis and Isaiah, whose friendship collapses under the weight of deception. When Curtis discovers Isaiah’s affair with Portia, the revelation shatters his fragile peace.

What started as suspicion—late-night messages, unconvincing alibis, and lingering scents of familiarity—culminates in undeniable proof: security footage of Isaiah and Portia together. The confrontation that follows is ice-cold and devastating.

Curtis’s quiet fury cuts deeper than any violence could. Isaiah’s guilt only deepens the wound, as Curtis realizes the betrayal wasn’t just romantic—it was personal, a corruption of trust. Now, their friendship has morphed into a cold war of vengeance and regret.

For Curtis, this becomes a turning point—a man reclaiming power by dismantling those who wronged him. For Isaiah, it’s the beginning of isolation, shame, and ruin.

Meanwhile, Ronnie’s power grab at the Quartermaine mansion turns the family’s legacy upside down. In one of the most ruthless moves in Quartermaine history, she uses her newfound inheritance to evict everyone from the mansion. Her justification? Rebuilding the family in her image.

But beneath her polished control lies obsession—an unrelenting need to erase generations of dysfunction and claim dominance.

Her actions ignite chaos: Tracy fights back with legal force, Brook Lynn rallies support, and Michael suspects a darker scheme involving ELQ’s finances.

The mansion becomes a battlefield of loyalty and deceit, a crumbling monument to a family defined by power struggles. By episode’s end, Ronnie’s crusade for control threatens to destroy the very family she claims to save.

As chaos erupts in the Quartermaine estate, Nathan’s warning to Willow adds another explosive layer. Investigating Drew’s shooting,

Nathan uncovers shocking new evidence suggesting the real killer is still in Port Charles—and connected to someone powerful. His discovery of links between Drew’s death and the infamous Five Poppies Project sends shivers through the PCPD.

When he learns that Willow’s name appears in encrypted files, Nathan realizes she’s in danger. His growing obsession with justice puts both their lives on the line, as shadowy forces close in.

What begins as a quest for redemption quickly spirals into a deadly race against time, exposing a conspiracy that could rock the city to its foundations.

But perhaps the most emotionally volatile story of the episode belongs to Lulu and Dante, whose fragile peace implodes when Lulu’s fear of losing her son to Britt Westbourne turns into obsession.

Convinced that Britt is manipulating Rocco, Lulu begins stalking their interactions, consumed by paranoia. Her confrontation with Britt in the hospital—public, raw, and humiliating—marks the breaking point.

Dante’s attempts to mediate fail as Lulu’s fixation deepens, leaving her isolated and unraveling. What began as a mother’s fear becomes a psychological descent, threatening to fracture her family for good.

By the end of this explosive midweek episode, Port Charles stands at a crossroads. Friendships are shattered, families are divided, and dark secrets edge closer to exposure. Curtis’s betrayal fuels vengeance, Ronnie’s ambition sparks a civil war, Nathan’s investigation uncovers deadly truths, and Lulu’s obsession teeters toward madness.

General Hospital reminds fans once again that in Port Charles, loyalty is fragile, love is dangerous, and every secret comes with a price.